BDBM718153 (5-Bromo-2-((R)-1-(isoquinolin-4-carbonyl)piperidin-3-yl)amino)-3-nitrophenyl)(6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)methanone::US20250042889, Example 7

SMILES CC1(C)C2CN(C(=O)c3cc(Br)cc([N+](=O)[O-])c3N[C@@H]3CCCN(C(=O)c4cncc5ccccc45)C3)CC21

InChI Key InChIKey=OAJUZSPQCGQWGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718153   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718153((5-Bromo-2-((R)-1-(isoquinolin-4-carbonyl)piperidi...)
Affinity DataIC50: 165nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent