BDBM718149 N-((1S,2R)-2-((4-bromo-2-nitro-6-(pyrrolidin-1-carbonyl)phenyl)amino)cyclohexyl) isoquinolin-4-formamide::US20250042889, Example 3

SMILES O=C(N[C@H]1CCCC[C@H]1Nc1c(C(=O)N2CCCC2)cc(Br)cc1[N+](=O)[O-])c1cncc2ccccc12

InChI Key InChIKey=ZYQQCSBSIUWUHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 718149   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandPNGBDBM718149(N-((1S,2R)-2-((4-bromo-2-nitro-6-(pyrrolidin-1-car...)
Affinity DataIC50: 30nMAssay Description:In this experiment, the activity of SARS-COV-2 3CLpro/Mpro protease was detected by fluorescence resonance energy transfer, and the half inhibitory c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
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