BDBM717931 US20250042857, Example B-38

SMILES C[C@@H](Nc1ccnc2cnc(N3CCS(=O)(=O)CC3)cc12)c1cccc(C(F)F)c1F

InChI Key InChIKey=NMQCIPHVFNLYPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 717931   

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Haihe Biopharma Co.

US Patent
LigandPNGBDBM717931(US20250042857, Example B-38)
Affinity DataIC50: 100nMAssay Description:Experimental reagents: KRASG12C/SOS binding kit (Cisbio, cat. 63ADK000CB16PEG); DMSO (Sigma, cat. D8418-1L); and 384-well white plate (PerkinElmer, c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717931(US20250042857, Example B-38)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed