BDBM717894 2-(Difluoromethyl)-4-(5-fluoro- 4-hydroxyl-3-(trifluoromethyl)- 4,5,6,7-tetrahydro-1H-indol-1- yl)benzonitrile::US20250042853, Example 107

SMILES N#Cc1ccc(-n2cc(C(F)(F)F)c3c2CCC(F)C3O)cc1C(F)F

InChI Key InChIKey=OLRIZQSMJSJOPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 717894   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717894(2-(Difluoromethyl)-4-(5-fluoro- 4-hydroxyl-3-(trif...)
Affinity DataIC50: 34nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717894(2-(Difluoromethyl)-4-(5-fluoro- 4-hydroxyl-3-(trif...)
Affinity DataIC50: 500nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent