BDBM717893 2-Fluoro-5-(2,5,5-trifluoro-4- hydroxyl-3-(thien-2-yl)-4,5,6,7- tetrahydro-1H-indol-1- yl)benzonitrile::US20250042853, Example 106

SMILES N#Cc1cc(-n2c(F)c(-c3cccs3)c3c2CCC(F)(F)C3O)ccc1F

InChI Key InChIKey=YLPTXIIZRHEBIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717893   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717893(2-Fluoro-5-(2,5,5-trifluoro-4- hydroxyl-3-(thien-2...)
Affinity DataIC50: 15nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/12/2025
Entry Details
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