BDBM717886 (R)-1-(3-(Difluoromethyl)-4- fluorophenyl)-5,5-difluoro-3- ((fluoromethyl)sulfonyl)- 4,5,6,7-tetrahydro-1H-indol-4- ol::US20250042853, Example 61

SMILES O=S(=O)(CF)c1cn(-c2ccc(F)c(C(F)F)c2)c2c1[C@@H](O)C(F)(F)CC2

InChI Key InChIKey=IMPWJDGPMUFPQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717886   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717886((R)-1-(3-(Difluoromethyl)-4- fluorophenyl)-5,5-dif...)
Affinity DataIC50: 500nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent