BDBM717867 (S)-4-(5,5-Difluoro-4-hydroxyl- 3-((trifluoromethyl)sulfonyl)- 4,5,6,7-tetrahydro-1H-indol-1- yl)-2- (difluoromethyl)benzonitrile::US20250042853, Example 35

SMILES N#Cc1ccc(-n2cc(S(=O)(=O)C(F)(F)F)c3c2CCC(F)(F)[C@H]3O)cc1C(F)F

InChI Key InChIKey=XEJXFTHJVBAFNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 717867   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717867((S)-4-(5,5-Difluoro-4-hydroxyl- 3-((trifluoromethy...)
Affinity DataIC50: 18nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717867((S)-4-(5,5-Difluoro-4-hydroxyl- 3-((trifluoromethy...)
Affinity DataIC50: 10nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent