BDBM717865 (S)-1-(3-Chloro-4- fluorophenyl)-5,5-difluoro-3- ((trifluoromethyl)sulfonyl)- 4,5,6,7-tetrahydro-1H-indol-4- ol::US20250042853, Example 33

SMILES O=S(=O)(c1cn(-c2ccc(F)c(Cl)c2)c2c1[C@H](O)C(F)(F)CC2)C(F)(F)F

InChI Key InChIKey=YQQDMELCCNWHLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 717865   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717865((S)-1-(3-Chloro-4- fluorophenyl)-5,5-difluoro-3- (...)
Affinity DataIC50: 41nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717865((S)-1-(3-Chloro-4- fluorophenyl)-5,5-difluoro-3- (...)
Affinity DataIC50: 52nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent