BDBM717861 (S)-4-(5,5-Difluoro-4-hydroxyl- 3-(methylsulfonyl)-4,5,6,7- tetrahydro-1H-indol-1-yl)-2- (difluoromethyl)benzonitrile::US20250042853, Example 29

SMILES N#Cc1ccc(-n2cc(S(C)(=O)=O)c3c2CCC(F)(F)[C@H]3O)cc1C(F)F

InChI Key InChIKey=VRVSXIXDKNKSSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717861   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717861((S)-4-(5,5-Difluoro-4-hydroxyl- 3-(methylsulfonyl)...)
Affinity DataIC50: 174nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent