BDBM717856 1-(3-Chloro-4-fluorophenyl)- 5,5-difluoro-3- (methylsulfonyl)-4,5,6,7- tetrahydro-1H-indol-4-ol::US20250042853, Example 24

SMILES CS(=O)(=O)c1cn(-c2ccc(F)c(Cl)c2)c2c1C(O)C(F)(F)CC2

InChI Key InChIKey=QXHMGJHADLWMJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717856   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717856(1-(3-Chloro-4-fluorophenyl)- 5,5-difluoro-3- (meth...)
Affinity DataIC50: 72nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent