BDBM717854 (S)-5-(3- ((Difluoromethyl)sulfonyl)- 2,5,5-trifluoroether-4-hydroxyl- 4,5,6,7-tetrahydro-1H-indol-1- yl)-2-fluorobenzonitrile::US20250042853, Example 22

SMILES N#Cc1cc(-n2c(F)c(S(=O)(=O)C(F)F)c3c2CCC(F)(F)[C@H]3O)ccc1F

InChI Key InChIKey=FTJXPVJKELYBAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717854   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717854((S)-5-(3- ((Difluoromethyl)sulfonyl)- 2,5,5-triflu...)
Affinity DataIC50: 86nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent