BDBM717853 (S)-3- ((Difluoromethyl)sulfonyl)-5,5- difluoro-1-(4-fluoro-3- (trifluoromethyl)phenyl)- 4,5,6,7-tetrahydro-1H-indol-4- ol::US20250042853, Example 21

SMILES O=S(=O)(c2cn(c1ccc(F)c(C(F)(F)F)c1)c3CCC(F)(F)[C@@H](O)c23)C(F)F

InChI Key InChIKey=BUHRAVPANRNXGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717853   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717853((S)-3- ((Difluoromethyl)sulfonyl)-5,5- difluoro-1-...)
Affinity DataIC50: 12nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent