BDBM717852 (S)-5,5-Difluoro-1-(4-fluoro-3- (trifluoromethyl)phenyl)-3- (methylsulfonyl)-4,5,6,7- tetrahydro-1H-indol-4-ol::US20250042853, Example 20

SMILES CS(=O)(=O)c3cn(c1ccc(F)c(C(F)(F)F)c1)c2CCC(F)(F)[C@@H](O)c23

InChI Key InChIKey=CWRWINMQJVTULO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717852   

TargetVascular endothelial growth factor A(Human)
Betta Pharmaceuticals Co.

US Patent
LigandPNGBDBM717852((S)-5,5-Difluoro-1-(4-fluoro-3- (trifluoromethyl)p...)
Affinity DataIC50: 39nMAssay Description:786-O cells in the logarithmic growth phase were inoculated into a 96-well plate at a cell concentration of 65,000 cells per ml of culture liquid, 18...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent