BDBM717591 5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methylene)piperidin-1-yl)-N-(1-methyl-1H-pyrazol-4-yl)picolinamide ::US20250034168, Compound 32

SMILES CCc1cc2ncc(C=C3CCN(c4ccc(C(=O)Nc5cnn(C)c5)nc4)CC3)cc2[nH]c1=O

InChI Key InChIKey=OUIIFMPZYMXWMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717591   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM717591(5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.190nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent