BDBM717448 3-{3-(4-fluorophenyl)-4-[6- (pyridin-2-yl)furo[2,3- d]pyrimidin-4-yl]-1H-pyrazol-1- yl}propanenitrile::US20250034159, Example 269

SMILES N#CCCn1cc(-c2ncnc3oc(-c4ccccn4)cc23)c(-c2ccc(F)cc2)n1

InChI Key InChIKey=DDGLOYLOXIZPJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717448   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717448(3-{3-(4-fluorophenyl)-4-[6- (pyridin-2-yl)furo[2,3...)
Affinity DataIC50: 0.0820nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent