BDBM717445 2,2-difluoro-3-{3-(4- fluorophenyl)-4-[6-(1-methyl- 1H-imidazol-4-yl)furo[2,3- d]pyrimidin-4-yl]-1H-pyrazol-1- yl}propan-1-ol::US20250034159, Example 266

SMILES Cn1cnc(-c2cc3c(-c4cn(CC(F)(F)CO)nc4-c4ccc(F)cc4)ncnc3o2)c1

InChI Key InChIKey=TXEXDLQTUVTADU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717445   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717445(2,2-difluoro-3-{3-(4- fluorophenyl)-4-[6-(1-methyl...)
Affinity DataIC50: 0.0940nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
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