BDBM717433 1-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-imidazol-4- yl)furo[2,3-d]pyrimidin-4-yl]- 1H-pyrazol-1-yl}-2- methylpropan-2-ol::US20250034159, Example 254

SMILES Cn1cnc(-c2cc3c(-c4cn(CC(C)(C)O)nc4-c4ccc(F)cc4)ncnc3o2)c1

InChI Key InChIKey=ABVUQIZKIKETAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717433   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717433(1-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-imidazol-...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent