BDBM717430 1-{4-[6-(1,3-dimethyl-1H- pyrazol-4-yl)furo[2,3- d]pyrimidin-4-yl]-3-(4- fluorophenyl)-1H-pyrazol-1-yl}- 2-methylpropan-2-ol::US20250034159, Example 251

SMILES Cc1nn(C)cc1-c1cc2c(-c3cn(CC(C)(C)O)nc3-c3ccc(F)cc3)ncnc2o1

InChI Key InChIKey=XFABPKYCGDBNNJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717430   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717430(1-{4-[6-(1,3-dimethyl-1H- pyrazol-4-yl)furo[2,3- d...)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent