BDBM717395 3-{3-(4-fluorophenyl)-4-[6-(1H- imidazol-4-yl)furo[2,3- d]pyrimidin-4-yl]-1H-pyrazol-1- yl}-1lambda6-thietane-1,1-dione::US20250034159, Example 216

SMILES O=S1(=O)CC(n2cc(-c3ncnc4oc(-c5c[nH]cn5)cc34)c(-c3ccc(F)cc3)n2)C1

InChI Key InChIKey=NTQBPEBGMCOHFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717395   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717395(3-{3-(4-fluorophenyl)-4-[6-(1H- imidazol-4-yl)furo...)
Affinity DataIC50: 0.0600nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent