BDBM717384 3-[3-(4-fluorophenyl)-4-(6-{3- [(4-methylpiperazin-1- yl)methyl]phenyl}furo[2,3- d]pyrimidin-4-yl)-1H-pyrazol-1- yl]-1lambda6-thietane-1,1-dione::US20250034159, Example 205

SMILES CN1CCN(Cc2cccc(-c3cc4c(-c5cn(C6CS(=O)(=O)C6)nc5-c5ccc(F)cc5)ncnc4o3)c2)CC1

InChI Key InChIKey=DETURULJMJCRHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717384   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717384(3-[3-(4-fluorophenyl)-4-(6-{3- [(4-methylpiperazin...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
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