BDBM717382 N-(3-{4-[1-(1,1-dioxo-126- thietan-3-yl)-3-(4-fluorophenyl)- 1H-pyrazol-4-yl]furo[2,3- d]pyrimidin-6-yl}phenyl)-N- methylmethanesulfonamide::US20250034159, Example 203

SMILES CN(c1cccc(-c2cc3c(-c4cn(C5CS(=O)(=O)C5)nc4-c4ccc(F)cc4)ncnc3o2)c1)S(C)(=O)=O

InChI Key InChIKey=XUGFUZPFXKLXBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717382   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717382(N-(3-{4-[1-(1,1-dioxo-126- thietan-3-yl)-3-(4-fluo...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent