BDBM71735 2-(2,6-dimethyl-4-morpholinyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)propanamide::2-(2,6-dimethylmorpholin-4-yl)-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)propanamide::2-(2,6-dimethylmorpholin-4-yl)-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)propanamide::2-(2,6-dimethylmorpholino)-N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)propionamide::MLS000056553::SMR000064660::cid_2999431

SMILES CC(C)(O)c1csc([S@](N)(=O)=NC(=O)Nc2c3c(cc4c2CCC4)CCC3)c1

InChI Key InChIKey=HKPCVWXXAVYXIP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 71735   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71735BDBM71735(US11724992, Example 204 | US11724992, Compound 183...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71735BDBM71735(US11724992, Example 204 | US11724992, Compound 183...)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71735BDBM71735(US11724992, Example 204 | US11724992, Compound 183...)
Affinity DataIC50: 600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent