BDBM71733 MLS000057502::N-(1,1-diketothiolan-3-yl)-2-[[4-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-methyl-acetamide::N-(1,1-dioxo-3-thiolanyl)-2-[[4-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-methylacetamide::N-(1,1-dioxothiolan-3-yl)-2-[[4-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-methylacetamide::N-[1,1-bis(oxidanylidene)thiolan-3-yl]-2-[[4-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-methyl-ethanamide::SMR000064124::cid_2999358

SMILES CC(C)(O)c1coc([S@@](N)(=O)=NC(=O)Nc2c3c(cc4c2CCC4)CCC3)c1

InChI Key InChIKey=DFZCUFBOHYRILQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71733   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71733BDBM71733(US11724992, Example 202 | US11724992, Compound 136...)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 71733BDBM71733(US11724992, Example 202 | US11724992, Compound 136...)
Affinity DataIC50: 3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent