BDBM717309 1-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-yl)-1H- pyrazol-1-yl]-2-methylpropan-2- ol::US20250034159, Example 130

SMILES CC(C)(O)Cn1cc(-c2ncnc3[nH]c(-c4ccccc4)nc23)c(-c2ccc(F)cc2)n1

InChI Key InChIKey=KKLYGIXHGBIVNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717309   

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM717309(1-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-yl)-...)
Affinity DataIC50: 0.120nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
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