BDBM717021 2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((S)-4-(5-hydroxy-6- methylpyrimidine-4-carbonyl)-2-methylpiperazin-1-yl)-8- oxopyrido[2,3-b]pyrazin-5(8H)-yl)-N-(2-chloro-4- (trifluoromethyl)phenyl)acetamide (single stereoisomer, first eluting compound as stereoisomer 1, cis)::US20250034136, Compound I-192

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)C[C@@H]2C)c(=O)c2nc(N3CC[C@H]4C[C@H]43)cnc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=KGOCDOPBJMKJFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717021   

LigandPNGBDBM717021(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((S...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
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