BDBM716337 US20250034108, Example 1

SMILES C[C@@](O)(CS(N)(=O)=O)c1cccc(-c2nnn(Cc3cc(OC(F)(F)F)ccc3F)n2)n1

InChI Key InChIKey=VSUGVLBZWPQVTR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 716337   

TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 716337BDBM716337(US20250034108, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.5 expressed in CHO-K1 cells preincubated for 3 mins followed by incubation under atrial fibrillation-mimicking condition at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 716337BDBM716337(US20250034108, Example 1)
Affinity DataIC50: 3.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 716337BDBM716337(US20250034108, Example 1)
Affinity DataIC50: 1.90E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 716337BDBM716337(US20250034108, Example 1)
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent