BDBM716233 US12209085, Example 217

SMILES C#Cc1cc(CN2C3CC2CN(c2ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn2)C3)ccn1

InChI Key InChIKey=PUCBZQNNYVJEDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716233   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM716233(US12209085, Example 217)
Affinity DataIC50: 0.350nMAssay Description:1. Experimental Purpose:The inhibitory activities of the series of compounds against Ret wt, VEGFR2, CCDC6-RET, Ret M918T, Ret V804L, and Ret V804M w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
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