BDBM716017 6-Amino-3-((1R,3S)-4'-chloro-3-(hydroxymethyl)- 1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-5'-yl)-2-fluoro-N,N-dimethylbenzamide 6-Amino-3-((1S,3R)-4'-chloro-3-(hydroxymethyl)- 1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-5'-yl)-2-fluoro-N,N-dimethylbenzamide::US12208088, Compound 259a

SMILES CN(C)C(=O)c1c(N)ccc(-c2cnc3c(c2Cl)[C@]2(CC[C@@H](CO)C2)CN3)c1F

InChI Key InChIKey=VQFVEKVOICRWIR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716017   

LigandPNGBDBM716017(6-Amino-3-((1R,3S)-4'-chloro-3-(hydroxymethyl)- 1'...)
Affinity DataKi:  6.10nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent