BDBM716009 (6-Amino-3-((1s,4s)-4'-chloro-4-hydroxy-1',2'- dihydrospiro[cyclohexane-1,3'-pyrrolo[2,3- b]pyridin]-5'-yl)-2-fluorophenyl)((R)-2-(1-methyl- 1H-pyrazol-4-yl)piperidin-1-yl)methanone (6-Amino-3-((1s,4s)-4'-chloro-4-hydroxy-1',2'- dihydrospiro[cyclohexane-1,3'-pyrrolo[2,3- b]pyridin]-5'-yl)-2-fluorophenyl)((S)-2-(1-methyl- 1H-pyrazol-4-yl)piperidin-1-yl)methanone::US12208088, Compound 254a

SMILES Cn1cc(C2CCCCN2C(=O)c2c(N)ccc(-c3cnc4c(c3)[C@]3(CC[C@H](O)CC3)CN4)c2F)cn1

InChI Key InChIKey=RYFBXMVFOIJJLZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716009   

LigandPNGBDBM716009((6-Amino-3-((1s,4s)-4'-chloro-4-hydroxy-1',2'- dih...)
Affinity DataKi:  5.20nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent