BDBM715906 (R)-(3-(1',2'-dihydrospiro[cyclopropane-1,3'- pyrrolo[2,3-b]pyridin]-5'-yl)-2-fluorophenyl)(2-(1- methyl-1H-pyrazol-4-yl)piperidin-1-yl)methanone (S)-(3-(1',2'-dihydrospiro[cyclopropane-1,3'- pyrrolo[2,3-b]pyridin]-5'-yl)-2-fluorophenyl)(2-(1- methyl-1H-pyrazol-4-yl)piperidin-1-yl)methanone::US12208088, Compound 175a

SMILES Cn1cc([C@H]2CCCCN2C(=O)c2cccc(-c3cnc4c(c3)C3(CC3)CN4)c2F)cn1

InChI Key InChIKey=WHBJGTRRXKMGBM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715906   

LigandPNGBDBM715906((R)-(3-(1',2'-dihydrospiro[cyclopropane-1,3'- pyrr...)
Affinity DataKi:  4.20nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent