BDBM715771 3-(3-(1S,3R)-4'-chloro-3-hydroxy-1',2'- dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-5'-yl)phenyl)-1-methylpyridin-2(1H)- one::US12208088, Compound 68c

SMILES Cn1cccc(-c2cccc(-c3cnc4c(c3Cl)[C@]3(CC[C@H](O)C3)CN4)c2)c1=O

InChI Key InChIKey=FCLUNEMVVNNWIS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715771   

LigandPNGBDBM715771(3-(3-(1S,3R)-4'-chloro-3-hydroxy-1',2'- dihydrospi...)
Affinity DataKi:  5.40nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent