BDBM714930 US20250026748, Compound 94

SMILES COc1ccc(C(F)(F)F)cc1-c1cn(CC(N)=O)c(=O)cc1C(=O)Nc1nnc(C#Cc2cc(C)[nH]n2)s1

InChI Key InChIKey=DBZPKSKPNAPVEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714930   

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandPNGBDBM714930(US20250026748, Compound 94)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent