BDBM714918 US20250026748, Compound 82

SMILES CNC(=O)Cn1cc(-c2cc(C(F)(F)F)ccc2OC)c(C(=O)Nc2nnc(C#Cc3cc(C)[nH]n3)s2)cc1=O

InChI Key InChIKey=HXHJBRMRQZGWDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714918   

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandPNGBDBM714918(US20250026748, Compound 82)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent