BDBM714832 6-(1-(3,4'-difluoro-[1,1'-biphenyl]- 4-yl)-2,2,2-trifluoroethyl)-4-((5-(5- fluoro-6-hydroxypyridin-2-yl)- 1,3,4-thiadiazol-2-yl)methyl)-4,6- diazaspiro[2.4]heptane-5,7-dione::US20250026745, Compound I-96

SMILES O=C1N(C(c2ccc(-c3ccc(F)cc3)cc2F)C(F)(F)F)C(=O)C2(CC2)N1Cc1nnc(-c2ccc(F)c(O)n2)s1

InChI Key InChIKey=HKKBDUKSPRTUTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714832   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714832(6-(1-(3,4'-difluoro-[1,1'-biphenyl]- 4-yl)-2,2,2-t...)
Affinity DataIC50: 3.11nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent