BDBM714830 4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-(1,1,1-trifluoropent-3- yn-2-yl)-4,6-diazaspiro[2.4]heptane- 5,7-dione::US20250026745, Compound I-94

SMILES CC#C[C@H](N1C(=O)N(Cc2nnc(-c3ccc(F)c(O)c3F)s2)C2(CC2)C1=O)C(F)(F)F

InChI Key InChIKey=OEDRVVHOLKTUSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714830   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714830(4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadi...)
Affinity DataIC50: 6.77nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent