BDBM714828 4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-(2,2-difluoroethyl)- 4,6-diazaspiro[2.4]heptane-5,7- dione::US20250026745, Compound I-92

SMILES O=C2N(CC(F)F)C(=O)C1(CC1)N2Cc4nnc(c3ccc(F)c(O)c3F)s4

InChI Key InChIKey=SKKJAGGXCQDUGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714828   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714828(4-((5-(2,4-difluoro-3- hydroxyphenyl)-1,3,4-thiadi...)
Affinity DataIC50: 14.3nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent