BDBM714827 (S)-4-((5-(4-fluoro-3-hydroxy-2- methylphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-(2,2,2-trifluoro-1- phenylethyl)-4,6- diazaspiro[2.4]heptane-5,7-dione::US20250026745, Compound I-91

SMILES Cc1c(-c2nnc(CN3C(=O)N([C@@H](c4ccccc4)C(F)(F)F)C(=O)C34CC4)s2)ccc(F)c1O

InChI Key InChIKey=UKTFTLRQUDRIHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714827   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714827((S)-4-((5-(4-fluoro-3-hydroxy-2- methylphenyl)-1,3...)
Affinity DataIC50: 4nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent