BDBM714790 (S)-4-((5-(2-chloro-4-fluoro-3- hydroxyphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-(2,2,2-trifluoro-1- phenylethyl)-4,6- diazaspiro[2.4]heptane-5,7-dione::US20250026745, Compound I-52

SMILES O=C1N([C@@H](c2ccccc2)C(F)(F)F)C(=O)C2(CC2)N1Cc1nnc(-c2ccc(F)c(O)c2Cl)s1

InChI Key InChIKey=BQDRUGHYEVVWJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714790   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714790((S)-4-((5-(2-chloro-4-fluoro-3- hydroxyphenyl)-1,3...)
Affinity DataIC50: 1.09nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent