BDBM714789 6-(tert-butyl)-4-((5-(2-chloro-4- fluoro-3-hydroxyphenyl)-1,3,4- thiadiazol-2-yl)methyl)-4,6- diazaspiro[2.4]heptane-5,7-dione::US20250026745, Compound I-50

SMILES CC(C)(C)N1C(=O)N(Cc2nnc(-c3ccc(F)c(O)c3Cl)s2)C2(CC2)C1=O

InChI Key InChIKey=FZRMEXTXLAGNKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714789   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714789(6-(tert-butyl)-4-((5-(2-chloro-4- fluoro-3-hydroxy...)
Affinity DataIC50: 4.60nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent