BDBM714771 (S)-4-((5-(2-chloro-4-fluoro-3- hydroxyphenyl)-1,3,4-thiadiazol-2- yl)methyl)-6-(1-phenylethyl)-4,6- diazaspiro[2.4]heptane-5,7-dione::US20250026745, Compound I-32

SMILES C[C@@H](c1ccccc1)N1C(=O)N(Cc2nnc(-c3ccc(F)c(O)c3Cl)s2)C2(CC2)C1=O

InChI Key InChIKey=ILMCXGBEQLBWJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714771   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Bluejay Therapeutics

US Patent
LigandPNGBDBM714771((S)-4-((5-(2-chloro-4-fluoro-3- hydroxyphenyl)-1,3...)
Affinity DataIC50: 3.72nMAssay Description:More specifically, recombinant 17β-HSD13 protein was assayed in a buffer containing 200 mM Tris pH 7.5, 0.01% Triton X-100, and 0.02% BSA into a 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent