BDBM714739 US20250026742, Example 38-1

SMILES [2H]c2c(c1ccc(CNC)cc1)noc2c5nc(c3ccc4c(c3)[C@@H](F)C(C)(C)S4(=O)=O)cnc5N

InChI Key InChIKey=FLYUMWCOKMPHSQ-WORMITQPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714739   

TargetSerine/threonine-protein kinase ATR(Human)
Suzhou Ark Biopharmaceutical Co.

US Patent
LigandPNGBDBM714739(US20250026742, Example 38-1)
Affinity DataIC50: 0.75nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent