BDBM714737 5-(5-amino-6-(5-(4-((1-methylpiperidin-4-yl)amino)methyl)phenyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-3-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b]thiophene 1,1-dioxide 36::US20250026742, Example 36

SMILES CN1CCC(NCc2ccc(-c3nnc(-c4nc(-c5ccc6c(c5)C(F)C(C)(C)S6(=O)=O)cnc4N)o3)cc2)CC1

InChI Key InChIKey=BSJFJVSNYFGURB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714737   

TargetSerine/threonine-protein kinase ATR(Human)
Suzhou Ark Biopharmaceutical Co.

US Patent
LigandPNGBDBM714737(5-(5-amino-6-(5-(4-((1-methylpiperidin-4-yl)amino)...)
Affinity DataIC50: 0.570nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
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