BDBM714707 1-(4-(5-(3-amino-6-(4-(isopropylsulfonyl)phenyl)pyrazin-2-yl)isoxazol-3-yl)benzyl)-3-ethylurea 6::US20250026742, Example 6

SMILES CCNC(=O)NCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1

InChI Key InChIKey=MUVLFXACOFTUSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 714707   

TargetSerine/threonine-protein kinase ATR(Human)
Suzhou Ark Biopharmaceutical Co.

US Patent
LigandPNGBDBM714707(1-(4-(5-(3-amino-6-(4-(isopropylsulfonyl)phenyl)py...)
Affinity DataIC50: 2.90nMAssay Description:Prepare various buffer systems required for the experiment:1. Prepare ATR reaction buffer containing 25 mM HEPES (Gibco, Cat #15630-080), 5 mM DTT (S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
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