BDBM714698 US20250026741, Compound #44

SMILES O=C1/C(=C/c2ccc(-c3ccc(O)c(C(=O)O)c3)o2)CC/C1=Cc1ccc(-c2ccc(O)c(C(=O)O)c2)o1

InChI Key InChIKey=QPBUDXJWVHWTJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 714698   

TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM714698(US20250026741, Compound #44)
Affinity DataIC50: 1.00E+3nMAssay Description:To test the synthesized compounds for their potential to inhibit SHP2 activity, a fluorescence intensity-based assay using 6,8-difluoro-4-methylumbel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM714698(US20250026741, Compound #44)
Affinity DataIC50: 1.05E+4nMAssay Description:To test the synthesized compounds for their potential to inhibit SHP2 activity, a fluorescence intensity-based assay using 6,8-difluoro-4-methylumbel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent