BDBM713759 2-(6-((5,6-dichloro-2-methyl- 1H-benzo[d]imidazol-1- yl)methyl)pyridin-3-yl)-5- (difluoromethyl)-1,3,4- oxadiazole::US12202823, Example 60

SMILES Cc1nc2cc(Cl)c(Cl)cc2n1Cc1ccc(-c2nnc(C(F)F)o2)cn1

InChI Key InChIKey=AEAYLPODYDXIQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713759   

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713759(2-(6-((5,6-dichloro-2-methyl- 1H-benzo[d]imidazol-...)
Affinity DataIC50: 42.3nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
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