BDBM713748 2-(difluoromethyl)-5-(6-((4- (2,6-difluorophenyl)-1H- 1,2,3-triazol-1- yl)methyl)pyridin-3-yl)- 1,3,4-oxadiazole::US12202823, Example 49

SMILES Fc1cccc(F)c1-c1cn(Cc2ccc(-c3nnc(C(F)F)o3)cn2)nn1

InChI Key InChIKey=ROOHTASNBJMHFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713748   

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713748(2-(difluoromethyl)-5-(6-((4- (2,6-difluorophenyl)-...)
Affinity DataIC50: 66.7nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
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