BDBM713743 2-(6-((4-(2-chlorophenyl)- 1H-1,2,3-triazol-1- yl)methyl)pyridin-3-yl)-5- (difluoromethyl)-1,3,4- oxadiazole::US12202823, Example 44

SMILES FC(F)c1nnc(-c2ccc(Cn3cc(-c4ccccc4Cl)nn3)nc2)o1

InChI Key InChIKey=YMHFKOVKYBAMCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713743   

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713743(2-(6-((4-(2-chlorophenyl)- 1H-1,2,3-triazol-1- yl)...)
Affinity DataIC50: 37.1nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent