BDBM713737 2-(difluoromethyl)-5-(4-(1- (4-phenyl-1H-1,2,3-triazol-1- yl)ethyl)phenyl)-1,3,4- oxadiazole::US12202823, Example 37

SMILES CC(c1ccc(-c2nnc(C(F)F)o2)cc1)n1cc(-c2ccccc2)nn1

InChI Key InChIKey=NEJKEXVTXWEAGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713737   

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713737(2-(difluoromethyl)-5-(4-(1- (4-phenyl-1H-1,2,3-tri...)
Affinity DataIC50: 149nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
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