BDBM713710 Mixture of three triazolic regioisomers::US12202823, Example 12

SMILES Cc3cccc4nnn(Cc2ccc(c1nnc(C(F)F)o1)cc2)c34

InChI Key InChIKey=UYXUEYOMEWZEFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713710   

TargetHistone deacetylase 6(Human)
Quimatryx

US Patent
LigandPNGBDBM713710(Mixture of three triazolic regioisomers | US122028...)
Affinity DataIC50: 190nMAssay Description:The buffer assay used in the inhibition hHDAC6 assay is: Hepes 50 mM, KCl 100 mM, Tween 20 0.001%, BSA 0.01%; pH=7.4. Study compound and hHDAC6 (BPS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent