BDBM713001 US20250019385, Example I-47

SMILES C[C@H](Oc1nc(-c2onc3c2CCC[C@@]32CCCc3sc(N)c(C#N)c32)nc2c1n(C)c(=O)n2[C@H]1CO[C@@H](C)C1)[C@@H]1CCCN1C

InChI Key InChIKey=GOOJBMJBYPTVLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 713001   

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713001(US20250019385, Example I-47)
Affinity DataIC50: 1nMAssay Description:This assay can be used to examine the potency with which compounds according to the invention binding to (mutated) KRAS inhibit the protein-protein i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent